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KMID : 0359320010410030351
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Korean Journal of Veterinary Research
2001 Volume.41 No. 3 p.351 ~ p.356
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Control of swine respiratory disease using egg yolk antibodies
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김종만/Kim, Jong Man
유한상/신나리/Yoo, Han Sang/Shin, Na Ri
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Abstract
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As an attempt to control respiratory disease in swine, specific immunologloblin Ys(IgYs)against bacterial pathogens of the diseases were produced and specificity of the IgYs was analysed with Western blot in the previous studies. In this studies, the immunoprotective effects of produced IgY were evaluated in the mice. Mice were challenged with minimal lethal doses of P multocida 3A and 4D, B bronchiseptica and A pleuropneumoniae serotype 2 after intraperitoneal administration of IgY and the protectivity by IgY was dose-dependent at the concentration of 100, 200 and 400 mg/ml. These results suggested that IgY could be a potential immunoprophylactic candidates against those pathogens in swine and apply and effective source of passive immunity for other disease in animals.
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KEYWORD
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Immunoprophylaxis, IgY, mouse
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